Ritonavir or lopinavir/ritonavir tremendously boost plasma concentrations of oxycodone in nutritious human volunteers resulting from inhibition of CYP3A4 and CYP2D6.[58] Rifampicin tremendously lessens plasma concentrations of oxycodone because of sturdy induction of CYP3A4.Should you or a person you know is thinking of using opioids for ache admin